Reactome | Receptor Mediated Mitophagy

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Receptor Mediated Mitophagy Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10445922
displayName	Receptor Mediated Mitophagy
eventOf	[Pathway:R-BTA-5205647] Mitophagy - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:20607] macroautophagy
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-8948039] FUNDC1 is phosphorylated by CK2 - Bos taurus [Reaction:R-BTA-8948143] p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 - Bos taurus [Reaction:R-BTA-8948139] p-S13-FUNDC1 is dephosphorylated by PGAM5 - Bos taurus [Reaction:R-BTA-8948136] ULK1 Translocates to the mitochondria - Bos taurus [Reaction:R-BTA-8948146] FUNDC1 is phosphorylated by ULK1 at Ser17 - Bos taurus [Reaction:R-BTA-8959573] Phosphorylated FUNDC1 links damaged mitochondria to LC3 - Bos taurus [Reaction:R-BTA-8959571] LC3 binds the autophagosome membrane Atg5-Atg12 complex - Bos taurus
inferredFrom	[Pathway:R-HSA-8934903] Receptor Mediated Mitophagy - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Receptor Mediated Mitophagy
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-8934903
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-5205647] Mitophagy
(inferredTo)	[Pathway:R-HSA-8934903] Receptor Mediated Mitophagy