Reactome | Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins

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Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins Show undefined attributes

catalystActivity	[CatalystActivity:10420123] peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity of Deglycosylation complex [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10420125
displayName	Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins
eventOf	[Pathway:R-BTA-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8850594] Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-BTA-8866894] Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins
output	[DefinedSet:R-ALL-8852852] (GlcNAc)2 (Man)9-5 [cytosol] [OtherEntity:R-ALL-1022114] unfolded protein [cytosol]
precedingEvent	[BlackBoxEvent:R-BTA-1022127] Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-8850594
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle
(inferredTo)	[Reaction:R-HSA-8850594] Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins

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