Reactome | PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10408522] protein serine/threonine kinase activity of PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-BTA-5693575] DNA-PKcs autophosphorylates - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10408521
displayName	PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
hasComponent	[OtherEntity:R-ALL-75165] DNA double-strand break ends [nucleoplasm] 2 × [Complex:R-BTA-5686711] PRKDC:XRCC5:XRCC6 heterotrimer [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-75907] PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm] - Homo sapiens
maxDepth	4
name	PRKDC:XRCC5:XRCC6:DNA DSB ends
producedByEvent	[Reaction:R-BTA-5693615] Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-75907
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-BTA-5693575] DNA-PKcs autophosphorylates
(physicalEntity)	[CatalystActivity:10408522] protein serine/threonine kinase activity of PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
(output)	[Reaction:R-BTA-5693615] Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis
(inferredTo)	[Complex:R-HSA-75907] PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]

Cite Us!