Reactome | PABPN1 [nucleoplasm]

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PABPN1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-BTA-9933582] CBCA:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm] - Bos taurus [Complex:R-BTA-9970402] Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] - Bos taurus [Complex:R-BTA-112164] upstream mRNA fragment:CPSF:PAP:PABPN1 complex [nucleoplasm] - Bos taurus [Complex:R-BTA-112162] intronless pre-mRNA cleavage complex [nucleoplasm] - Bos taurus
consumedByEvent	[BlackBoxEvent:R-BTA-9970189] PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS - Bos taurus [BlackBoxEvent:R-BTA-9970320] PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS - Bos taurus [BlackBoxEvent:R-BTA-9970318] PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS - Bos taurus [Reaction:R-BTA-77591] Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10339334
displayName	PABPN1 [nucleoplasm]
endCoordinate	306
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-72008] PABPN1 [nucleoplasm] - Homo sapiens
maxDepth	1
name	PABPN1 PABPN1 Q28165
producedByEvent	[BlackBoxEvent:R-BTA-9970428] CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS) - Bos taurus [BlackBoxEvent:R-BTA-9970431] CPA complex components dissociate from polyadenylated pre-mRNA (proximal 3'UTR PAS) - Bos taurus [BlackBoxEvent:R-BTA-9970429] CPA complex components dissociate from polyadenylated pre-mRNA (intronic PAS) - Bos taurus [Reaction:R-BTA-77593] Cleavage and polyadenylation of Intronless Pre-mRNA - Bos taurus
referenceEntity	[ReferenceGeneProduct:uniprot:Q28165] UniProt:Q28165
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48898] Bos taurus
stId	R-BTA-72008
startCoordinate	2

Referrals

(hasComponent)	[Complex:R-BTA-9933582] CBCA:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm] [Complex:R-BTA-9935798] CBCA:ZFC3H1:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm] [Complex:R-BTA-9970402] Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] [Complex:R-BTA-9970389] Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] [Complex:R-BTA-9970319] Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] [Complex:R-BTA-112164] upstream mRNA fragment:CPSF:PAP:PABPN1 complex [nucleoplasm] [Complex:R-BTA-112162] intronless pre-mRNA cleavage complex [nucleoplasm] [Complex:R-BTA-72021] Cleavage and Polyadenylation Complex [nucleoplasm]
(output)	[BlackBoxEvent:R-BTA-9970428] CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS) [BlackBoxEvent:R-BTA-9970431] CPA complex components dissociate from polyadenylated pre-mRNA (proximal 3'UTR PAS) [BlackBoxEvent:R-BTA-9970429] CPA complex components dissociate from polyadenylated pre-mRNA (intronic PAS) [Reaction:R-BTA-77593] Cleavage and polyadenylation of Intronless Pre-mRNA
(input)	[BlackBoxEvent:R-BTA-9970189] PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS [BlackBoxEvent:R-BTA-9970320] PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS [BlackBoxEvent:R-BTA-9970318] PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS [Reaction:R-BTA-77591] Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-72008] PABPN1 [nucleoplasm]

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