Reactome | USP21 deubiquitinates RIPK1,DDX58

Schema > Reaction > Entries

USP21 deubiquitinates RIPK1,DDX58 Show undefined attributes

catalystActivity	[CatalystActivity:10407718] cysteine-type deubiquitinase activity of USP21:PolyUb-RIPK1, PolyUb-DDX58 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10407720
displayName	USP21 deubiquitinates RIPK1,DDX58
eventOf	[Pathway:R-BTA-5689880] Ub-specific processing proteases - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5690159] USP21 deubiquitinates RIPK1,DDX58 - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-BTA-6783163] USP21:PolyUb-RIPK1, PolyUb-DDX58 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	USP21 deubiquitinates RIPK1,DDX58
output	[DefinedSet:R-BTA-5689096] PolyUb [cytosol] [Complex:R-BTA-6783081] USP21:RIPK1,DDX58 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-5690159
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-5689880] Ub-specific processing proteases
(inferredTo)	[Reaction:R-HSA-5690159] USP21 deubiquitinates RIPK1,DDX58

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