Reactome | UCH proteinases

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UCH proteinases Show undefined attributes

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10445610
displayName	UCH proteinases
eventOf	[Pathway:R-BTA-5688426] Deubiquitination - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-5665871] ADRM1 binds 26S proteasome - Bos taurus [Reaction:R-BTA-5665854] ADRM1:26S proteaseome binds UCHL5 - Bos taurus [Reaction:R-BTA-5689544] UCHL5 binds INO80 complex - Bos taurus [Reaction:R-BTA-5689630] BAP1 binds BAP1-interacting complex - Bos taurus [Reaction:R-BTA-5689649] BAP1 binds BRCA1:BARD1 - Bos taurus [Reaction:R-BTA-5690785] BAP1 binds Ub-HCFC1 - Bos taurus [Reaction:R-BTA-5690759] BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 - Bos taurus [Reaction:R-BTA-5690790] Histone H2A is dubiquitinated by the PR-DUB complex - Bos taurus [Reaction:R-BTA-5690319] UCHL1, UCHL3 cleave ubiquitin adducts - Bos taurus [Reaction:R-BTA-5690808] UCHL3, SENP8 cleave NEDD8 - Bos taurus
inferredFrom	[Pathway:R-HSA-5689603] UCH proteinases - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	UCH proteinases
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-5689603
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-5688426] Deubiquitination
(inferredTo)	[Pathway:R-HSA-5689603] UCH proteinases

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