Reactome | UCH proteinases

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UCH proteinases Show undefined attributes

authored	[InstanceEdit:5688433] Jupe, Steve, 2015-04-16
created	[InstanceEdit:5689562] Jupe, Steve, 2015-04-23
dbId	5689603
displayName	UCH proteinases
edited	[InstanceEdit:8869523] Jupe, Steve, 2016-05-05
eventOf	[Pathway:R-HSA-5688426] Deubiquitination - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-5665871] ADRM1 binds 26S proteasome - Homo sapiens [Reaction:R-HSA-5665854] ADRM1:26S proteaseome binds UCHL5 - Homo sapiens [Reaction:R-HSA-5689544] UCHL5 binds INO80 complex - Homo sapiens [Reaction:R-HSA-5689630] BAP1 binds BAP1-interacting complex - Homo sapiens [Reaction:R-HSA-5689649] BAP1 binds BRCA1:BARD1 - Homo sapiens [Reaction:R-HSA-5690785] BAP1 binds Ub-HCFC1 - Homo sapiens [Reaction:R-HSA-5690759] BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 - Homo sapiens [Reaction:R-HSA-5690790] Histone H2A is dubiquitinated by the PR-DUB complex - Homo sapiens [Reaction:R-HSA-5690319] UCHL1, UCHL3 cleave ubiquitin adducts - Homo sapiens [Reaction:R-HSA-5690808] UCHL3, SENP8 cleave NEDD8 - Homo sapiens [Reaction:R-HSA-2179291] UCHL5, USP15 deubiquitinate TGFBR1 - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5689914] A genomic and functional inventory of deubiquitinating enzymes [LiteratureReference:5689873] Polyubiquitin binding and disassembly by deubiquitinating enzymes
modified	[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name	UCH proteinases
orthologousEvent	[Pathway:R-PFA-5689603] UCH proteinases - Plasmodium falciparum [Pathway:R-SCE-5689603] UCH proteinases - Saccharomyces cerevisiae [Pathway:R-SPO-5689603] UCH proteinases - Schizosaccharomyces pombe [Pathway:R-DDI-5689603] UCH proteinases - Dictyostelium discoideum [Pathway:R-CEL-5689603] UCH proteinases - Caenorhabditis elegans [Pathway:R-DME-5689603] UCH proteinases - Drosophila melanogaster [Pathway:R-GGA-5689603] UCH proteinases - Gallus gallus [Pathway:R-XTR-5689603] UCH proteinases - Xenopus tropicalis [Pathway:R-DRE-5689603] UCH proteinases - Danio rerio [Pathway:R-SSC-5689603] UCH proteinases - Sus scrofa [Pathway:R-BTA-5689603] UCH proteinases - Bos taurus [Pathway:R-CFA-5689603] UCH proteinases - Canis familiaris [Pathway:R-RNO-5689603] UCH proteinases - Rattus norvegicus [Pathway:R-MMU-5689603] UCH proteinases - Mus musculus
releaseDate	2016-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8871339] Meldal, Birgit, 2016-05-16
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-5689603
summation	[Summation:5689591] DUBs of the Ub C-terminal Hydrolase (UCH) family are thiol p...

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[Pathway:R-HSA-5688426] Deubiquitination

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