Reactome | p-S MAPK6,4 binds MAPKAPK5

Schema > Reaction > Entries

p-S MAPK6,4 binds MAPKAPK5 Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10406471
displayName	p-S MAPK6,4 binds MAPKAPK5
eventOf	[Pathway:R-BTA-5687128] MAPK6/MAPK4 signaling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-5687094] p-S MAPK6,4 phosphorylate MAPKAPK5 - Bos taurus
inferredFrom	[Reaction:R-HSA-5687091] p-S MAPK6,4 binds MAPKAPK5 - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-2562517] MAPKAPK5 [nucleoplasm] [DefinedSet:R-BTA-5687052] p-S MAPK6,4 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	p-S MAPK6,4 binds MAPKAPK5
output	[Complex:R-BTA-5687063] p-S MAPK6,4:MAKPAPK5 [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-BTA-5687107] MAPK4,6 translocate to nucleus - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-5687091
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-5687128] MAPK6/MAPK4 signaling
(precedingEvent)	[Reaction:R-BTA-5687094] p-S MAPK6,4 phosphorylate MAPKAPK5
(inferredTo)	[Reaction:R-HSA-5687091] p-S MAPK6,4 binds MAPKAPK5

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