Reactome | Melanin biosynthesis

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Melanin biosynthesis Show undefined attributes

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10445608
displayName	Melanin biosynthesis
eventOf	[Pathway:R-BTA-71291] Metabolism of amino acids and derivatives - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:12141] melanin biosynthetic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-BTA-5662662] Tyrosinase oxidises tyrosine to dopaquinone - Bos taurus [Reaction:R-BTA-5662692] Dopa is oxidized to dopaquinone by TYR - Bos taurus [Reaction:R-BTA-5662660] Dopachrome is transformed to DHICA by DCT - Bos taurus [Reaction:R-BTA-8878581] TYRP1 oxidises DHICA to IQCA - Bos taurus [BlackBoxEvent:R-BTA-5663050] DHI and DHICA polymerize forming eumelanin - Bos taurus
inferredFrom	[Pathway:R-HSA-5662702] Melanin biosynthesis - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Melanin biosynthesis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-5662702
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-71291] Metabolism of amino acids and derivatives
(inferredTo)	[Pathway:R-HSA-5662702] Melanin biosynthesis

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