Reactome | phospho-STAT3 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-BTA-9701454] p-Y705,S727-STAT3 dimer [cytosol] - Bos taurus [Complex:R-BTA-9701454] p-Y705,S727-STAT3 dimer [cytosol] - Bos taurus
consumedByEvent	[Reaction:R-BTA-9701525] p-Y705,S727-STAT3 dimerizes - Bos taurus [Reaction:R-BTA-9701525] p-Y705,S727-STAT3 dimerizes - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10374754
displayName	phospho-STAT3 [cytosol]
endCoordinate	770
hasModifiedResidue	[ModifiedResidue:10374752] O-phospho-L-serine at 727 (in Homo sapiens) [ModifiedResidue:10374679] O4'-phospho-L-tyrosine at 705 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-539048] p-Y705,S727-STAT3 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-BTA-1112740] Tyrosine/serine phosphorylated STAT1, STAT3 [cytosol] - Bos taurus
name	phospho-STAT3 p-Y705,S727-STAT3 F1MX38
producedByEvent	[BlackBoxEvent:R-BTA-9701524] STAT3 is phosphorylated downstream of active ALK - Bos taurus
referenceEntity	[ReferenceGeneProduct:uniprot:F1MX38] UniProt:F1MX38
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48898] Bos taurus
stId	R-BTA-539048
startCoordinate	2

(input)	[Reaction:R-BTA-9701525] p-Y705,S727-STAT3 dimerizes
(output)	[BlackBoxEvent:R-BTA-9701524] STAT3 is phosphorylated downstream of active ALK
(hasComponent)	[Complex:R-BTA-9701454] p-Y705,S727-STAT3 dimer [cytosol]
(hasMember)	[DefinedSet:R-BTA-1112740] Tyrosine/serine phosphorylated STAT1, STAT3 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-539048] p-Y705,S727-STAT3 [cytosol]

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