Reactome | p-SLP-76 binds VAV

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10364296
displayName	p-SLP-76 binds VAV
eventOf	[Pathway:R-BTA-114604] GPVI-mediated activation cascade - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-430158] p-SLP-76 binds VAV - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-202175] phospho-LCP2 [cytosol] [DefinedSet:R-BTA-430172] VAV1,2,3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	p-SLP-76 binds VAV
output	[Complex:R-BTA-430155] p-SLP-76:VAV [cytosol]
precedingEvent	[Reaction:R-BTA-429449] Syk activation leads to SLP-76 activation - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-430158
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-114604] GPVI-mediated activation cascade
(inferredTo)	[Reaction:R-HSA-430158] p-SLP-76 binds VAV

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