Reactome | PIAS3 SUMOylates MITF with SUMO1

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PIAS3 SUMOylates MITF with SUMO1 Show undefined attributes

catalystActivity	[CatalystActivity:10392043] SUMO transferase activity of PIAS3 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10392045
displayName	PIAS3 SUMOylates MITF with SUMO1
eventOf	[Pathway:R-BTA-3232118] SUMOylation of transcription factors - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:4162] protein sumoylation
inferredFrom	[Reaction:R-HSA-3232162] PIAS3 SUMOylates MITF with SUMO1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-201592] MITF [nucleoplasm] 2 × [Complex:R-BTA-2993783] SUMO1:C93-UBE2I [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PIAS3 SUMOylates MITF with SUMO1
output	[EntityWithAccessionedSequence:R-BTA-3232153] MITF [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-BTA-912481] UBE2I [nucleoplasm]
precedingEvent	[Reaction:R-BTA-2993780] Transfer of SUMO1 from E1 to UBE2I (UBC9) - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-3232162
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-3232118] SUMOylation of transcription factors
(inferredTo)	[Reaction:R-HSA-3232162] PIAS3 SUMOylates MITF with SUMO1

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