Reactome | KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10355507] ATP binding activity of KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-BTA-9650859] ABCC8:Meglitinides [plasma membrane] - Bos taurus
consumedByEvent	[Reaction:R-BTA-9650858] Meglitinides bind ABCC8 - Bos taurus [Reaction:R-BTA-9652580] SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) - Bos taurus [Reaction:R-BTA-265682] KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10355502
displayName	KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]
hasComponent	4 × [Complex:R-BTA-6790054] ABCC8:Mg2+:ADP [plasma membrane] 4 × [EntityWithAccessionedSequence:R-BTA-265561] KCNJ11 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-265734] KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane] - Homo sapiens
maxDepth	4
name	KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-265734
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-BTA-9650858] Meglitinides bind ABCC8 [Reaction:R-BTA-9652580] SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) [Reaction:R-BTA-265682] KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel
(hasComponent)	[Complex:R-BTA-9650859] ABCC8:Meglitinides [plasma membrane] [Complex:R-BTA-9652593] ABCC8:SU drugs [plasma membrane]
(physicalEntity)	[CatalystActivity:10355507] ATP binding activity of KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]
(inferredTo)	[Complex:R-HSA-265734] KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]

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