Reactome | INS [secretory granule lumen]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:1462052] secretory granule lumen
componentOf	[Complex:R-BTA-265073] 6xProinsulin:2xZn2+:1xCa2+ [secretory granule lumen] - Bos taurus [Complex:R-BTA-265073] 6xProinsulin:2xZn2+:1xCa2+ [secretory granule lumen] - Bos taurus [Complex:R-BTA-265073] 6xProinsulin:2xZn2+:1xCa2+ [secretory granule lumen] - Bos taurus [Complex:R-BTA-265073] 6xProinsulin:2xZn2+:1xCa2+ [secretory granule lumen] - Bos taurus [Complex:R-BTA-265073] 6xProinsulin:2xZn2+:1xCa2+ [secretory granule lumen] - Bos taurus [Complex:R-BTA-265073] 6xProinsulin:2xZn2+:1xCa2+ [secretory granule lumen] - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10355312
displayName	INS [secretory granule lumen]
endCoordinate	110
hasModifiedResidue	[IntraChainCrosslinkedResidue:10355291] Intra-chain Crosslink via L-cystine (cross-link) at 31 and 96 (in Homo sapiens) [IntraChainCrosslinkedResidue:10355292] Intra-chain Crosslink via L-cystine (cross-link) at 43 and 109 (in Homo sapiens) [IntraChainCrosslinkedResidue:10337425] Intra-chain Crosslink via L-cystine (cross-link) at 95 and 100 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-264984] 6xHC-INS(25-110) [secretory granule lumen] - Homo sapiens
maxDepth	1
name	INS 6xHC-INS(25-110) A5PJB2
referenceEntity	[ReferenceGeneProduct:uniprot:A5PJB2] UniProt:A5PJB2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48898] Bos taurus
stId	R-BTA-264984
startCoordinate	25

(hasComponent)	[Complex:R-BTA-265073] 6xProinsulin:2xZn2+:1xCa2+ [secretory granule lumen]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-264984] 6xHC-INS(25-110) [secretory granule lumen]