Reactome | M6PR transports activated ARSA to the lysosome

Schema > Reaction > Entries

M6PR transports activated ARSA to the lysosome Show undefined attributes

catalystActivity	[CatalystActivity:10388332] cargo receptor activity of M6PR [transport vesicle]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:161320] lysosomal lumen
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10388334
displayName	M6PR transports activated ARSA to the lysosome
eventOf	[Pathway:R-BTA-9840310] Glycosphingolipid catabolism - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-1606807] ARSA removes sulfate from PSAP(195-273):Sulfatide - Bos taurus [Reaction:R-BTA-9840949] ARSA removes sulfate from SM3 - Bos taurus
inferredFrom	[Reaction:R-HSA-2248891] M6PR transports activated ARSA to the lysosome - Homo sapiens
input	[Complex:R-BTA-1614355] active ARSA:Ca2+ [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	M6PR transports activated ARSA to the lysosome
output	[Complex:R-BTA-1606814] active ARSA:Ca2+ [lysosomal lumen]
precedingEvent	[Reaction:R-BTA-1614362] SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-2248891
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9840310] Glycosphingolipid catabolism
(precedingEvent)	[Reaction:R-BTA-9840949] ARSA removes sulfate from SM3 [Reaction:R-BTA-1606807] ARSA removes sulfate from PSAP(195-273):Sulfatide
(inferredTo)	[Reaction:R-HSA-2248891] M6PR transports activated ARSA to the lysosome

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