Reactome | Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen

Schema > BlackBoxEvent > Entries

Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol [Compartment:161320] lysosomal lumen
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10353991
displayName	Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen
eventOf	[Pathway:R-BTA-196791] Vitamin D (calciferol) metabolism - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-BTA-350158] LGMN hydrolyzes GC, releasing CUBN and 25(OH)D - Bos taurus
goBiologicalProcess	[GO_BiologicalProcess:258911] intracellular lipid transport
inferredFrom	[BlackBoxEvent:R-HSA-209760] Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen - Homo sapiens
input	[Complex:R-BTA-350092] CUBN:GC:25(OH)D [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen
output	[Complex:R-BTA-350085] CUBN:GC:25(OH)D [lysosomal lumen]
precedingEvent	[Reaction:R-BTA-350168] LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D - Bos taurus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-209760
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-196791] Vitamin D (calciferol) metabolism
(precedingEvent)	[BlackBoxEvent:R-BTA-350158] LGMN hydrolyzes GC, releasing CUBN and 25(OH)D
(inferredTo)	[BlackBoxEvent:R-HSA-209760] Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen

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