Reactome | YAP1 binds ZO-2 (TJP2)

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10385656
displayName	YAP1 binds ZO-2 (TJP2)
eventOf	[Pathway:R-BTA-2028269] Signaling by Hippo - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-2064406] Translocation of YAP1:ZO-2 (TJP2) to the nucleus - Bos taurus
inferredFrom	[Reaction:R-HSA-2064421] YAP1 binds ZO-2 (TJP2) - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-2064412] TJP2 [cytosol] [EntityWithAccessionedSequence:R-BTA-1253345] YAP1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	YAP1 binds ZO-2 (TJP2)
output	[Complex:R-BTA-2064400] YAP1:TJP2 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-2064421
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-2028269] Signaling by Hippo
(precedingEvent)	[Reaction:R-BTA-2064406] Translocation of YAP1:ZO-2 (TJP2) to the nucleus
(inferredTo)	[Reaction:R-HSA-2064421] YAP1 binds ZO-2 (TJP2)

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