Reactome | Caspase-mediated cleavage of alpha adducin

Schema > Reaction > Entries

Caspase-mediated cleavage of alpha adducin Show undefined attributes

catalystActivity	[CatalystActivity:10351848] cysteine-type endopeptidase activity of Caspase-3 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10351870
displayName	Caspase-mediated cleavage of alpha adducin
eventOf	[Pathway:R-BTA-264870] Caspase-mediated cleavage of cytoskeletal proteins - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-201608] Caspase-mediated cleavage of alpha adducin - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-201623] ADD1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Caspase-mediated cleavage of alpha adducin
output	[EntityWithAccessionedSequence:R-BTA-202891] ADD1(1-633) [cytosol] [EntityWithAccessionedSequence:R-BTA-202890] ADD1(634-737) [cytosol]
precedingEvent	[Reaction:R-BTA-114252] Cleavage of Procaspase-3 by the apoptosome - Bos taurus [Reaction:R-BTA-418845] Activation of caspase-3 - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-201608
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-264870] Caspase-mediated cleavage of cytoskeletal proteins
(inferredTo)	[Reaction:R-HSA-201608] Caspase-mediated cleavage of alpha adducin

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