Reactome | PP2A [cytosol]

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PP2A [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:10404464] protein serine/threonine phosphatase activity of PP2A [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-BTA-432144] p-PECAM:PP2A [plasma membrane] - Bos taurus [Complex:R-BTA-196222] p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] - Bos taurus [Complex:R-BTA-195250] AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] - Bos taurus [Complex:R-BTA-375305] Kinetochore [cytosol] - Bos taurus
consumedByEvent	[Reaction:R-BTA-389532] PP2A binds CTLA4 dimer - Bos taurus [Reaction:R-BTA-8857925] Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 - Bos taurus [Reaction:R-BTA-432143] PECAM-1 binds PP2A - Bos taurus [Reaction:R-BTA-195251] Assembly of the destruction complex - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10342626
displayName	PP2A [cytosol]
hasComponent	[CandidateSet:R-BTA-196216] PP2A regulatory subunit B56 [cytosol] [CandidateSet:R-BTA-165977] PP2A-catalytic subunit C [cytosol] [CandidateSet:R-BTA-165990] PP2A-subunit A [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-196206] PP2A [cytosol] - Homo sapiens
maxDepth	3
name	PP2A
producedByEvent	[Reaction:R-BTA-388833] Phosphorylation of CTLA-4 - Bos taurus [Reaction:R-BTA-201685] Beta-catenin is released from the destruction complex - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-196206
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-BTA-432143] PECAM-1 binds PP2A [Reaction:R-BTA-389532] PP2A binds CTLA4 dimer [Reaction:R-BTA-195251] Assembly of the destruction complex [Reaction:R-BTA-8857925] Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307
(hasComponent)	[Complex:R-BTA-432144] p-PECAM:PP2A [plasma membrane] [Complex:R-BTA-196222] p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Complex:R-BTA-3601577] p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] [Complex:R-BTA-195297] p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Complex:R-BTA-195250] AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] [Complex:R-BTA-389533] CTLA4 dimer:PP2A [plasma membrane] [Complex:R-BTA-375305] Kinetochore [cytosol]
(output)	[Reaction:R-BTA-388833] Phosphorylation of CTLA-4 [Reaction:R-BTA-201685] Beta-catenin is released from the destruction complex
(physicalEntity)	[CatalystActivity:10404464] protein serine/threonine phosphatase activity of PP2A [cytosol]
(inferredTo)	[Complex:R-HSA-196206] PP2A [cytosol]

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