Reactome | EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-BTA-8866253] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10347852
displayName	EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane]
hasComponent	2 × [DefinedSet:R-BTA-9624194] EGF-like ligands [extracellular region] 2 × [Complex:R-BTA-182964] p-Y371-CBL:GRB2 [cytosol] 2 × [EntityWithAccessionedSequence:R-BTA-179803] phospho-p-6Y-EGFR [plasma membrane] 2 × [DefinedSet:R-BTA-113595] Ub [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-182945] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] - Homo sapiens
maxDepth	3
name	EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2
producedByEvent	[Reaction:R-BTA-183036] Ubiquitination of stimulated EGFR (CBL:GRB2) - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-182945
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-BTA-8866253] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane]
(output)	[Reaction:R-BTA-183036] Ubiquitination of stimulated EGFR (CBL:GRB2)
(inferredTo)	[Complex:R-HSA-182945] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane]

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