Reactome | DDX58 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-BTA-1169379] ISG15 targets [cytosol] - Bos taurus
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-BTA-6782841] USP25:DDX58 [cytosol] - Bos taurus [Complex:R-BTA-936557] ISG15:DDX58 conjugate [cytosol] - Bos taurus
consumedByEvent	[Reaction:R-BTA-9927247] ISGylation of DDX58 (RIG-I) - Bos taurus [Reaction:R-BTA-8985153] OASL binds DDX58 - Bos taurus [Reaction:R-BTA-936563] ISGylation of DDX58 - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10370474
displayName	DDX58 [cytosol]
endCoordinate	925
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-168917] DDX58 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-BTA-5690188] RIPK1, DDX58 [cytosol] - Bos taurus [DefinedSet:R-BTA-5696897] RCE1, CDC25A, DDX58, IFIH1 [cytosol] - Bos taurus
name	DDX58 F1MKU1
producedByEvent	[BlackBoxEvent:R-BTA-936390] CYLD mediated deubiquitination of DDX58 (RIG-I) - Bos taurus
referenceEntity	[ReferenceGeneProduct:uniprot:F1MKU1] UniProt:F1MKU1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48898] Bos taurus
stId	R-BTA-168917
startCoordinate	1

(hasMember)	[DefinedSet:R-BTA-5690188] RIPK1, DDX58 [cytosol] [DefinedSet:R-BTA-5696897] RCE1, CDC25A, DDX58, IFIH1 [cytosol]
(hasComponent)	[Complex:R-BTA-6782841] USP25:DDX58 [cytosol] [Complex:R-BTA-9927392] ISGylated DDX58 [cytosol] [Complex:R-BTA-8985113] OASL:DDX58 [cytosol] [Complex:R-BTA-936557] ISG15:DDX58 conjugate [cytosol]
(input)	[Reaction:R-BTA-9927247] ISGylation of DDX58 (RIG-I) [Reaction:R-BTA-8985153] OASL binds DDX58 [Reaction:R-BTA-936563] ISGylation of DDX58
(hasCandidate)	[CandidateSet:R-BTA-1169379] ISG15 targets [cytosol]
(output)	[BlackBoxEvent:R-BTA-936390] CYLD mediated deubiquitination of DDX58 (RIG-I)
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-168917] DDX58 [cytosol]

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