Reactome | Toll-like Receptor Cascades

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Toll-like Receptor Cascades Show undefined attributes

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10443616
displayName	Toll-like Receptor Cascades
eventOf	[Pathway:R-BTA-168249] Innate Immune System - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:258822] toll-like receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-BTA-1679131] Trafficking and processing of endosomal TLR - Bos taurus [Pathway:R-BTA-168142] Toll Like Receptor 10 (TLR10) Cascade - Bos taurus [Pathway:R-BTA-168164] Toll Like Receptor 3 (TLR3) Cascade - Bos taurus [Pathway:R-BTA-168176] Toll Like Receptor 5 (TLR5) Cascade - Bos taurus [Pathway:R-BTA-168181] Toll Like Receptor 7/8 (TLR7/8) Cascade - Bos taurus [Pathway:R-BTA-168138] Toll Like Receptor 9 (TLR9) Cascade - Bos taurus [Pathway:R-BTA-166016] Toll Like Receptor 4 (TLR4) Cascade - Bos taurus [Pathway:R-BTA-181438] Toll Like Receptor 2 (TLR2) Cascade - Bos taurus [Pathway:R-BTA-5686938] Regulation of TLR by endogenous ligand - Bos taurus
inferredFrom	[Pathway:R-HSA-168898] Toll-like Receptor Cascades - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	9
name	Toll-like Receptor Cascades
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-168898
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-168249] Innate Immune System
(inferredTo)	[Pathway:R-HSA-168898] Toll-like Receptor Cascades

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