Reactome | MAP3K7 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-BTA-6782955] MAP3K7:TAB1 [cytosol] - Bos taurus [Complex:R-BTA-9645445] ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] - Bos taurus [Complex:R-BTA-9645445] ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10365750
displayName	MAP3K7 [cytosol]
endCoordinate	606
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-168156] MAP3K7 [cytosol] - Homo sapiens
maxDepth	1
name	MAP3K7 A2VDU3
referenceEntity	[ReferenceGeneProduct:uniprot:A2VDU3] UniProt:A2VDU3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48898] Bos taurus
stId	R-BTA-168156
startCoordinate	1

(hasComponent)	[Complex:R-BTA-6782955] MAP3K7:TAB1 [cytosol] [Complex:R-BTA-8947970] TAK1 complex [plasma membrane] [Complex:R-BTA-9645445] ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] [Complex:R-BTA-446878] TAK1 complex [cytosol]
(activeUnit)	[CatalystActivity:10390554] protein serine/threonine kinase activity of DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] [CatalystActivity:10368485] MAP kinase kinase kinase activity of TAK1 complex [cytosol] [CatalystActivity:10370616] protein serine/threonine kinase activity of activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] [CatalystActivity:10433097] MAP kinase kinase kinase kinase activity of ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] [CatalystActivity:10370636] MAP kinase kinase kinase kinase activity of p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-168156] MAP3K7 [cytosol]