Reactome | SREBP1A,1C,2 translocates to the nucleus

Schema > BlackBoxEvent > Entries

SREBP1A,1C,2 translocates to the nucleus Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10380565
displayName	SREBP1A,1C,2 translocates to the nucleus
eventOf	[Pathway:R-BTA-1655829] Regulation of cholesterol biosynthesis by SREBP (SREBF) - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-2065539] SREBP1A,1C,2:Importin beta-1 dissociates - Bos taurus
goBiologicalProcess	[GO_BiologicalProcess:11054] protein import into nucleus
inferredFrom	[BlackBoxEvent:R-HSA-1655831] SREBP1A,1C,2 translocates to the nucleus - Homo sapiens
input	[Complex:R-BTA-2065556] SREBP1A,1C,2:Importin beta-1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SREBP1A,1C,2 translocates to the nucleus SREBF1A,1C,2 translocates to the nucleus
output	[Complex:R-BTA-2065543] SREBP1A,1C,2:Importin beta-1 [nucleoplasm]
precedingEvent	[Reaction:R-BTA-2065550] SREBP1A,1C,2 binds Importin beta-1 - Bos taurus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-1655831
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-1655829] Regulation of cholesterol biosynthesis by SREBP (SREBF)
(precedingEvent)	[Reaction:R-BTA-2065539] SREBP1A,1C,2:Importin beta-1 dissociates
(inferredTo)	[BlackBoxEvent:R-HSA-1655831] SREBP1A,1C,2 translocates to the nucleus

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