Reactome | ZBP1(DAI) mediated induction of type I IFNs

Schema > Pathway > Entries

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10443696
displayName	ZBP1(DAI) mediated induction of type I IFNs
eventOf	[Pathway:R-BTA-1834949] Cytosolic sensors of pathogen-associated DNA - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-BTA-1606341] IRF3 mediated activation of type 1 IFN - Bos taurus [Pathway:R-BTA-1810476] RIP-mediated NFkB activation via ZBP1 - Bos taurus
inferredFrom	[Pathway:R-HSA-1606322] ZBP1(DAI) mediated induction of type I IFNs - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	ZBP1(DAI) mediated induction of type I IFNs
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-1606322
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-1834949] Cytosolic sensors of pathogen-associated DNA
(inferredTo)	[Pathway:R-HSA-1606322] ZBP1(DAI) mediated induction of type I IFNs

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