Reactome | NEU1,4 hydrolyze PSAP(195-273):GM3:PE

Schema > Reaction > Entries

NEU1,4 hydrolyze PSAP(195-273):GM3:PE Show undefined attributes

catalystActivity	[CatalystActivity:10379856] exo-alpha-sialidase activity of NEU1,4 [lysosomal lumen]
category	transition
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10379858
displayName	NEU1,4 hydrolyze PSAP(195-273):GM3:PE
eventOf	[Pathway:R-BTA-9840310] Glycosphingolipid catabolism - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-1606312] GLB1 hydrolyzes SapB/C:LacCer - Bos taurus
inferredFrom	[Reaction:R-HSA-1605724] NEU1,4 hydrolyze PSAP(195-273):GM3:PE - Homo sapiens
input	[SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen] [Complex:R-BTA-9840821] PSAP(195-273):GM3:PE [lysosomal lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	NEU1,4 hydrolyze PSAP(195-273):GM3:PE
output	[SimpleEntity:R-ALL-428639] Neu5Ac [lysosomal lumen] [Complex:R-BTA-9840818] PSAP(195-273):LacCer:PE [lysosomal lumen]
precedingEvent	[Reaction:R-BTA-1605595] bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 - Bos taurus [Reaction:R-BTA-9840470] PSAP(195-273) dimer:PE binds and mobilizes ligands - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-1605724
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9840310] Glycosphingolipid catabolism
(precedingEvent)	[Reaction:R-BTA-1606312] GLB1 hydrolyzes SapB/C:LacCer
(inferredTo)	[Reaction:R-HSA-1605724] NEU1,4 hydrolyze PSAP(195-273):GM3:PE

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