Reactome | CBL dissociates from ubiquitinated p-SPRY2

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CBL dissociates from ubiquitinated p-SPRY2 Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10376168
displayName	CBL dissociates from ubiquitinated p-SPRY2
eventOf	[Pathway:R-BTA-1295596] Spry regulation of FGF signaling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1295621] CBL dissociates from ubiquitinated p-SPRY2 - Homo sapiens
input	[Complex:R-BTA-934572] Ub:Y55/Y227-pSPRY2:CBL [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CBL dissociates from ubiquitinated p-SPRY2
output	[EntityWithAccessionedSequence:R-BTA-112199] CBL [cytosol] [Complex:R-BTA-1370875] Ub-(Y55/Y227)p-SPRY2 [plasma membrane]
precedingEvent	[Reaction:R-BTA-934604] Phosphorylated SPRY2 is ubiquitinated by CBL - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-1295621
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-1295596] Spry regulation of FGF signaling
(inferredTo)	[Reaction:R-HSA-1295621] CBL dissociates from ubiquitinated p-SPRY2

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