Reactome | 2xHC-GLRX [cytosol]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:10340625] glutathione disulfide oxidoreductase activity of 2xHC-GLRX [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-BTA-111746] glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10340607
displayName	2xHC-GLRX [cytosol]
endCoordinate	106
hasModifiedResidue	[IntraChainCrosslinkedResidue:10340605] Intra-chain Crosslink via L-cystine (cross-link) at 23 and 26 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-111740] 2xHC-GLRX [cytosol] - Homo sapiens
maxDepth	1
name	2xHC-GLRX G8JKV3
producedByEvent	[Reaction:R-BTA-8866405] RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) - Bos taurus [Reaction:R-BTA-111742] RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) - Bos taurus
referenceEntity	[ReferenceGeneProduct:uniprot:G8JKV3] UniProt:G8JKV3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48898] Bos taurus
stId	R-BTA-111740
startCoordinate	2

(output)	[Reaction:R-BTA-8866405] RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) [Reaction:R-BTA-111742] RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)
(input)	[Reaction:R-BTA-111746] glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized)
(physicalEntity)	[CatalystActivity:10340625] glutathione disulfide oxidoreductase activity of 2xHC-GLRX [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-111740] 2xHC-GLRX [cytosol]

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