Reactome | 2-OH-ATVL [cytosol]

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-9756136] PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV - Homo sapiens
created	[InstanceEdit:9756320] Jassal, Bijay, 2021-10-13
dbId	9756330
displayName	2-OH-ATVL [cytosol]
inDisease	false
maxDepth	1
memberOf	[DefinedSet:R-ALL-9757150] ATVs [cytosol]
modified	[InstanceEdit:9756762] Jassal, Bijay, 2021-10-18
name	2-OH-ATVL 2-hydroxyatorvastatin lactone
producedByEvent	[BlackBoxEvent:R-RNO-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL - Rattus norvegicus [BlackBoxEvent:R-MMU-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL - Mus musculus [BlackBoxEvent:R-HSA-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL - Homo sapiens [Reaction:R-GGA-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL - Gallus gallus [Reaction:R-XTR-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL - Xenopus tropicalis [Reaction:R-DRE-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL - Danio rerio [Reaction:R-SSC-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL - Sus scrofa [Reaction:R-BTA-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL - Bos taurus [Reaction:R-CFA-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL - Canis familiaris [Reaction:R-RNO-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL - Rattus norvegicus [Reaction:R-MMU-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL - Mus musculus [Reaction:R-HSA-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL - Homo sapiens
referenceEntity	[ReferenceMolecule:chebi:180932] 2-hydroxyatorvastatin lactone [ChEBI:180932]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-9756330

(output)	[Reaction:R-GGA-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL [Reaction:R-XTR-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL [Reaction:R-DRE-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL [Reaction:R-SSC-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL [Reaction:R-BTA-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL [Reaction:R-CFA-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL [Reaction:R-RNO-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL [Reaction:R-MMU-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL [Reaction:R-HSA-9756138] CYP3A4 monooxygenates ATVL to 2-OH-ATVL [BlackBoxEvent:R-RNO-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL [BlackBoxEvent:R-MMU-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL [BlackBoxEvent:R-HSA-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL
(input)	[Reaction:R-HSA-9756136] PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV
(hasMember)	[DefinedSet:R-ALL-9757150] ATVs [cytosol]

2-OH-ATVL [cytosol] Show undefined attributes

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