Reactome | 2-OH-ATV [cytosol]

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2-OH-ATV [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[BlackBoxEvent:R-RNO-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL - Rattus norvegicus [BlackBoxEvent:R-MMU-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL - Mus musculus [BlackBoxEvent:R-HSA-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL - Homo sapiens
created	[InstanceEdit:9756320] Jassal, Bijay, 2021-10-13
crossReference	[DatabaseIdentifier:12021187] Mondo:0005439
dbId	9756322
disease	[Disease:9705580] familial hypercholesterolemia [Disease:9611304] cardiovascular system disease
displayName	2-OH-ATV [cytosol]
inDisease	true
maxDepth	1
name	2-OH-ATV 2-hydroxyatorvastatin ortho-hydroxyatorvastatin
producedByEvent	[Reaction:R-HSA-9756136] PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV - Homo sapiens [Reaction:R-GGA-9756169] CYP3A4 monooxygenates ATV to 2-OH-ATV - Gallus gallus [Reaction:R-XTR-9756169] CYP3A4 monooxygenates ATV to 2-OH-ATV - Xenopus tropicalis [Reaction:R-DRE-9756169] CYP3A4 monooxygenates ATV to 2-OH-ATV - Danio rerio [Reaction:R-SSC-9756169] CYP3A4 monooxygenates ATV to 2-OH-ATV - Sus scrofa [Reaction:R-BTA-9756169] CYP3A4 monooxygenates ATV to 2-OH-ATV - Bos taurus [Reaction:R-CFA-9756169] CYP3A4 monooxygenates ATV to 2-OH-ATV - Canis familiaris [Reaction:R-RNO-9756169] CYP3A4 monooxygenates ATV to 2-OH-ATV - Rattus norvegicus [Reaction:R-MMU-9756169] CYP3A4 monooxygenates ATV to 2-OH-ATV - Mus musculus [Reaction:R-HSA-9756169] CYP3A4 monooxygenates ATV to 2-OH-ATV - Homo sapiens
referenceEntity	[ReferenceTherapeutic:iuphar.ligand:6705] o-hydroxyatorvastatin [Guide to Pharmacology:6705]
schemaClass	ChemicalDrug
stId	R-ALL-9756322

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