Reactome | Anti-MET TKIs [cytosol]

Schema > CandidateSet > Entries

Anti-MET TKIs [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-GGA-9735965] HGF:MET dimer:TKIs [plasma membrane] - Gallus gallus [Complex:R-GGA-9735965] HGF:MET dimer:TKIs [plasma membrane] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Gallus gallus [Reaction:R-GGA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Gallus gallus [Reaction:R-XTR-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Xenopus tropicalis [Reaction:R-XTR-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Xenopus tropicalis [Reaction:R-DRE-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Danio rerio [Reaction:R-DRE-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Danio rerio [Reaction:R-SSC-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Sus scrofa [Reaction:R-SSC-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Sus scrofa [Reaction:R-BTA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Bos taurus [Reaction:R-BTA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Bos taurus [Reaction:R-CFA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Canis familiaris [Reaction:R-CFA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Canis familiaris [Reaction:R-RNO-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Rattus norvegicus [Reaction:R-RNO-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Rattus norvegicus [Reaction:R-MMU-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Mus musculus [Reaction:R-MMU-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Mus musculus [Reaction:R-HSA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Homo sapiens [Reaction:R-HSA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET - Homo sapiens
created	[InstanceEdit:9735963] Orlic-Milacic, Marija, 2021-07-06
dbId	9735962
displayName	Anti-MET TKIs [cytosol]
hasCandidate	[ChemicalDrug:R-ALL-9735985] amuvatinib [cytosol] [ChemicalDrug:R-ALL-9735989] OMO-1 [cytosol] [ChemicalDrug:R-ALL-9735957] tivantinib [cytosol]
hasMember	[ChemicalDrug:R-ALL-9735960] AMG-337 [cytosol] [ChemicalDrug:R-ALL-9735961] BMS-777607 [cytosol] [ChemicalDrug:R-ALL-9669718] cabozantinib [cytosol] [ChemicalDrug:R-ALL-9735954] capmatinib [cytosol] [ChemicalDrug:R-ALL-9699597] crizotinib [cytosol] [ChemicalDrug:R-ALL-9700418] foretinib [cytosol] [ChemicalDrug:R-ALL-9735969] glesatinib [cytosol] [ChemicalDrug:R-ALL-9735990] golvatinib [cytosol] [ChemicalDrug:R-ALL-9735991] MK-2461 [cytosol] [ChemicalDrug:R-ALL-9735951] PHA-665752 [cytosol] [ChemicalDrug:R-ALL-9735983] savolitinib [cytosol] [ChemicalDrug:R-ALL-9735966] SGX-523 [cytosol] [ChemicalDrug:R-ALL-9735956] SU11274 [cytosol] [ChemicalDrug:R-ALL-9735987] tepotinib [cytosol]
inDisease	false
maxDepth	2
modified	[InstanceEdit:9750178] Orlic-Milacic, Marija, 2021-08-10
name	Anti-MET TKIs
schemaClass	CandidateSet
stId	R-ALL-9735962

Referrals

(input)	[Reaction:R-GGA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET [Reaction:R-XTR-9735946] Anti-MET small tyrosine kinase inhibitors bind MET [Reaction:R-DRE-9735946] Anti-MET small tyrosine kinase inhibitors bind MET [Reaction:R-SSC-9735946] Anti-MET small tyrosine kinase inhibitors bind MET [Reaction:R-BTA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET [Reaction:R-CFA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET [Reaction:R-RNO-9735946] Anti-MET small tyrosine kinase inhibitors bind MET [Reaction:R-MMU-9735946] Anti-MET small tyrosine kinase inhibitors bind MET [Reaction:R-HSA-9735946] Anti-MET small tyrosine kinase inhibitors bind MET
(hasComponent)	[Complex:R-GGA-9735965] HGF:MET dimer:TKIs [plasma membrane] [Complex:R-XTR-9735965] HGF:MET dimer:TKIs [plasma membrane] [Complex:R-SSC-9735965] HGF:MET dimer:TKIs [plasma membrane] [Complex:R-CFA-9735965] HGF:MET dimer:TKIs [plasma membrane] [Complex:R-MMU-9735965] HGF:MET dimer:TKIs [plasma membrane] [Complex:R-DRE-9735965] HGF:MET dimer:TKIs [plasma membrane] [Complex:R-RNO-9735965] HGF:MET dimer:TKIs [plasma membrane] [Complex:R-BTA-9735965] HGF:MET dimer:TKIs [plasma membrane] [Complex:R-HSA-9735965] HGF:MET dimer:TKIs [plasma membrane]
(activeUnit)	[NegativeRegulation:9736001] Negative regulation by 'HGF:MET dimer:TKIs [plasma membrane]'

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