Reactome | brigatinib [cytosol]

Schema > ChemicalDrug > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[FailedReaction:R-HSA-9715356] brigatinib-resistant ALK mutants don't bind brigatinib - Homo sapiens
created	[InstanceEdit:9699603] Rothfels, Karen, 2020-09-14
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9699601
disease	[Disease:1500689] cancer
displayName	brigatinib [cytosol]
inDisease	true
maxDepth	1
memberOf	[DefinedSet:R-ALL-9699973] type I ALK-binding TKIs [cytosol]
name	brigatinib Alunbrig® AP26113 AP-26113 compound 11q [PMID: 27144831]
referenceEntity	[ReferenceTherapeutic:iuphar.ligand:7741] brigatinib [Guide to Pharmacology:7741]
schemaClass	ChemicalDrug
stId	R-ALL-9699601

(input)	[FailedReaction:R-HSA-9715356] brigatinib-resistant ALK mutants don't bind brigatinib
(hasMember)	[DefinedSet:R-ALL-9699973] type I ALK-binding TKIs [cytosol]

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