Reactome | cobimetinib [cytosol]

Schema > ChemicalDrug > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9657528] Rothfels, Karen, 2019-08-08
crossReference	[DatabaseIdentifier:12020751] Mondo:0005105 [DatabaseIdentifier:9657526] ChEBI:90851
dbId	9657527
disease	[Disease:1614289] melanoma
displayName	cobimetinib [cytosol]
inDisease	true
literatureReference	[LiteratureReference:9657419] Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers
maxDepth	1
memberOf	[CandidateSet:R-ALL-9657574] single mechanism MAP2K1/2 inhibitors [cytosol]
name	cobimetinib
referenceEntity	[ReferenceTherapeutic:iuphar.ligand:7626] cobimetinib [Guide to Pharmacology:7626]
schemaClass	ChemicalDrug
stId	R-ALL-9657527

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