Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
Polymer
>
Entries
(HA)50 [plasma membrane]
Show undefined attributes
Go to Details
compartment
[Compartment:876] plasma membrane
consumedByEvent
[BlackBoxEvent:R-HSA-2160906] 20kDa HA fragments are translocated to lysosomes - Homo sapiens
created
[InstanceEdit:2160887] Jassal, B, 2012-03-05
crossReference
[DatabaseIdentifier:9667752] ChEBI:64024
dbId
2160894
displayName
(HA)50 [plasma membrane]
inDisease
false
maxDepth
2
maxUnitCount
50
modified
[InstanceEdit:9667753] D'Eustachio, Peter, 2019-11-16
name
(HA)50
Hyaluronic acid
Hyaluronan
producedByEvent
[BlackBoxEvent:R-GGA-2160892] HYAL2 hydrolyses HA into 20kDa fragments - Gallus gallus
[BlackBoxEvent:R-DRE-2160892] HYAL2 hydrolyses HA into 20kDa fragments - Danio rerio
[BlackBoxEvent:R-SSC-2160892] HYAL2 hydrolyses HA into 20kDa fragments - Sus scrofa
[BlackBoxEvent:R-BTA-2160892] HYAL2 hydrolyses HA into 20kDa fragments - Bos taurus
[BlackBoxEvent:R-CFA-2160892] HYAL2 hydrolyses HA into 20kDa fragments - Canis familiaris
[BlackBoxEvent:R-RNO-2160892] HYAL2 hydrolyses HA into 20kDa fragments - Rattus norvegicus
[BlackBoxEvent:R-MMU-2160892] HYAL2 hydrolyses HA into 20kDa fragments - Mus musculus
[BlackBoxEvent:R-HSA-2160892] HYAL2 hydrolyses HA into 20kDa fragments - Homo sapiens
[BlackBoxEvent:R-HSA-9941244] ROS/RNS degrade HA - Homo sapiens
[BlackBoxEvent:R-CEL-9941055] SPAM1 randomly cleaves HA - Caenorhabditis elegans
[BlackBoxEvent:R-XTR-9941055] SPAM1 randomly cleaves HA - Xenopus tropicalis
[BlackBoxEvent:R-DRE-9941055] SPAM1 randomly cleaves HA - Danio rerio
[Reaction:R-DDI-5693356] CEMIP hydrolyzes HA - Dictyostelium discoideum
[BlackBoxEvent:R-GGA-9941055] SPAM1 randomly cleaves HA - Gallus gallus
[Reaction:R-GGA-5693356] CEMIP hydrolyzes HA - Gallus gallus
[BlackBoxEvent:R-SSC-9941055] SPAM1 randomly cleaves HA - Sus scrofa
[Reaction:R-SSC-5693356] CEMIP hydrolyzes HA - Sus scrofa
[BlackBoxEvent:R-BTA-9941055] SPAM1 randomly cleaves HA - Bos taurus
[Reaction:R-BTA-5693356] CEMIP hydrolyzes HA - Bos taurus
[BlackBoxEvent:R-CFA-9941055] SPAM1 randomly cleaves HA - Canis familiaris
[Reaction:R-CFA-5693356] CEMIP hydrolyzes HA - Canis familiaris
[BlackBoxEvent:R-RNO-9941055] SPAM1 randomly cleaves HA - Rattus norvegicus
[Reaction:R-RNO-5693356] CEMIP hydrolyzes HA - Rattus norvegicus
[BlackBoxEvent:R-MMU-9941055] SPAM1 randomly cleaves HA - Mus musculus
[Reaction:R-MMU-5693356] CEMIP hydrolyzes HA - Mus musculus
[Reaction:R-HSA-5693356] CEMIP hydrolyzes HA - Homo sapiens
[BlackBoxEvent:R-HSA-9941055] SPAM1 randomly cleaves HA - Homo sapiens
repeatedUnit
[SimpleEntity:R-ALL-9014801] GlcA-b1,3-GlcNAc [plasma membrane]
schemaClass
Polymer
stId
R-ALL-2160894
updateTrackers
[UpdateTracker:9897329] Update Tracker - [Polymer:2160894] (HA)50 [plasma membrane] - v62:[add_removeRepeatedUnit]
Referrals
(updatedInstance)
[UpdateTracker:9897329] Update Tracker - [Polymer:2160894] (HA)50 [plasma membrane] - v62:[add_removeRepeatedUnit]
(output)
[BlackBoxEvent:R-GGA-2160892] HYAL2 hydrolyses HA into 20kDa fragments
[BlackBoxEvent:R-DRE-2160892] HYAL2 hydrolyses HA into 20kDa fragments
[BlackBoxEvent:R-SSC-2160892] HYAL2 hydrolyses HA into 20kDa fragments
[BlackBoxEvent:R-BTA-2160892] HYAL2 hydrolyses HA into 20kDa fragments
[BlackBoxEvent:R-CFA-2160892] HYAL2 hydrolyses HA into 20kDa fragments
[BlackBoxEvent:R-RNO-2160892] HYAL2 hydrolyses HA into 20kDa fragments
[BlackBoxEvent:R-MMU-2160892] HYAL2 hydrolyses HA into 20kDa fragments
[BlackBoxEvent:R-HSA-2160892] HYAL2 hydrolyses HA into 20kDa fragments
[BlackBoxEvent:R-CEL-9941055] SPAM1 randomly cleaves HA
[BlackBoxEvent:R-XTR-9941055] SPAM1 randomly cleaves HA
[BlackBoxEvent:R-DRE-9941055] SPAM1 randomly cleaves HA
[Reaction:R-DDI-5693356] CEMIP hydrolyzes HA
[BlackBoxEvent:R-GGA-9941055] SPAM1 randomly cleaves HA
[Reaction:R-GGA-5693356] CEMIP hydrolyzes HA
[BlackBoxEvent:R-SSC-9941055] SPAM1 randomly cleaves HA
[Reaction:R-SSC-5693356] CEMIP hydrolyzes HA
[BlackBoxEvent:R-BTA-9941055] SPAM1 randomly cleaves HA
[Reaction:R-BTA-5693356] CEMIP hydrolyzes HA
[BlackBoxEvent:R-CFA-9941055] SPAM1 randomly cleaves HA
[Reaction:R-CFA-5693356] CEMIP hydrolyzes HA
[BlackBoxEvent:R-RNO-9941055] SPAM1 randomly cleaves HA
[Reaction:R-RNO-5693356] CEMIP hydrolyzes HA
[BlackBoxEvent:R-MMU-9941055] SPAM1 randomly cleaves HA
[Reaction:R-MMU-5693356] CEMIP hydrolyzes HA
[BlackBoxEvent:R-HSA-9941244] ROS/RNS degrade HA
[Reaction:R-HSA-5693356] CEMIP hydrolyzes HA
[BlackBoxEvent:R-HSA-9941055] SPAM1 randomly cleaves HA
(input)
[BlackBoxEvent:R-HSA-2160906] 20kDa HA fragments are translocated to lysosomes
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text