Reactome | SU5402 [cytosol]

Schema > ChemicalDrug > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2054051] Rothfels, K, 2012-01-12
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992 [DatabaseIdentifier:9628151] ChEBI:63449
dbId	2054052
disease	[Disease:1500689] cancer
displayName	SU5402 [cytosol]
inDisease	true
literatureReference	[LiteratureReference:2054033] Blocking of FGFR signaling inhibits breast cancer cell proliferation through downregulation of D-type cyclins
maxDepth	1
memberOf	[DefinedSet:R-ALL-2045079] Tyrosine kinase inhibitors of FGFR1 fusion mutants [cytosol] [DefinedSet:R-ALL-2077403] Tyrosine kinase inhibitors of FGFR2 mutants [cytosol] [DefinedSet:R-ALL-2023441] Tyrosine kinase inhibitors of overexpressed FGFR1 [cytosol] [DefinedSet:R-ALL-2077416] Tyrosine kinase inhibitors of FGFR3 mutants [cytosol]
modified	[InstanceEdit:9757288] Jassal, Bijay, 2021-10-28
name	SU5402
referenceEntity	[ReferenceTherapeutic:pubchem.compound:5289418] SU5402 [PubChem Compound:5289418]
schemaClass	ChemicalDrug
stId	R-ALL-2054052
summation	[Summation:2054053] SU5402 is an ATP-competitive FGFR and VEGFR inhibitor that i...

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