Reactome | Negative regulation by 'CALM:OspC3:CASP4:LPS:GBPs [cytosol]'

Schema > NegativeRegulation > Entries

activeUnit	[EntityWithAccessionedSequence:R-SFL-9956663] OspC3 [cytosol] - Shigella flexneri
activity	[GO_MolecularFunction:15235] cysteine-type endopeptidase inhibitor activity
created	[InstanceEdit:9960494] Shamovsky, Veronica, 2025-07-14
dbId	9960498
displayName	Negative regulation by 'CALM:OspC3:CASP4:LPS:GBPs [cytosol]'
goBiologicalProcess	[GO_BiologicalProcess:422917] negative regulation of endopeptidase activity
regulatedEntity	[Reaction:R-HSA-9947908] CASP4 autocatalysis on the bacterial surface - Homo sapiens
regulator	[Complex:R-HSA-9960484] CALM:OspC3:CASP4:LPS:GBPs [cytosol]
schemaClass	NegativeRegulation

(regulation)	[RegulationReference:9960499] Negative regulation by 'CALM:OspC3:CASP4:LPS:GBPs [cytosol]' Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis
(regulatedBy)	[Reaction:R-HSA-9947908] CASP4 autocatalysis on the bacterial surface

Cite Us!