Reactome | Negative regulation by 'CASP4:SERPINB1 [cytosol]'

Schema > NegativeRegulation > Entries

activeUnit	[EntityWithAccessionedSequence:R-HSA-8962908] SERPINB1 [cytosol] - Homo sapiens
created	[InstanceEdit:9953128] Shamovsky, Veronica, 2025-05-28
dbId	9953129
displayName	Negative regulation by 'CASP4:SERPINB1 [cytosol]'
goBiologicalProcess	[GO_BiologicalProcess:9910369] negative regulation of non-canonical inflammasome complex assembly
modified	[InstanceEdit:9960517] Shamovsky, Veronica, 2025-07-14
regulatedEntity	[Polymerisation:R-HSA-9947940] CASP4 forms dimers on the bacterial surface - Homo sapiens [Polymerisation:R-HSA-9686271] CASP4 dimerizes - Homo sapiens
regulator	[Complex:R-HSA-9948159] CASP4:SERPINB1 [cytosol]
schemaClass	NegativeRegulation

(regulatedBy)	[Polymerisation:R-HSA-9947940] CASP4 forms dimers on the bacterial surface [Polymerisation:R-HSA-9686271] CASP4 dimerizes
(regulation)	[RegulationReference:9953127] Negative regulation by 'CASP4:SERPINB1 [cytosol]' SERPINB1-mediated checkpoint of inflammatory caspase activation

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