Reactome | ZNF598 Is a Quality Control Sensor of Collided Ribosomes

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author	[Person:9908503] Juszkiewicz, S [Person:9937370] Chandrasekaran, V [Person:5358487] Lin, Z [Person:9949671] Kraatz, S [Person:8855070] Ramakrishnan, V [Person:5250556] Hegde, RS
created	[InstanceEdit:9949679] May, Bruce, 2025-05-24
dbId	9949683
displayName	ZNF598 Is a Quality Control Sensor of Collided Ribosomes
journal	Mol Cell
pages	469-481.e7
pubMedIdentifier	30293783
schemaClass	LiteratureReference
title	ZNF598 Is a Quality Control Sensor of Collided Ribosomes
url	http://www.ncbi.nlm.nih.gov/pubmed/30293783
volume	72
year	2018

(literatureReference)	[Pathway:R-HSA-9948299] Ribosome-associated quality control [Pathway:R-HSA-9954716] ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA [Reaction:R-HSA-9948301] ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit [Reaction:R-HSA-9948317] ZNF598 and Ub:UBE2D1,2,3 bind stalled 80S ribosome
(author)	[Person:9937370] Chandrasekaran, V [Person:5250556] Hegde, RS [Person:8855070] Ramakrishnan, V [Person:5358487] Lin, Z [Person:9949671] Kraatz, S [Person:9908503] Juszkiewicz, S

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