Reactome | Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast

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Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast Show undefined attributes

author	[Person:9941975] Hilton, HN [Person:9941982] Graham, JD [Person:9941983] Kantimm, S [Person:9941980] Santucci, N [Person:9941974] Cloosterman, D [Person:9941976] Huschtscha, LI [Person:9941978] Mote, PA [Person:9941979] Clarke, CL
created	[InstanceEdit:9941981] Orlic-Milacic, Marija, 2025-03-12
dbId	9941977
displayName	Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast
journal	Mol Cell Endocrinol
pages	191-201
pubMedIdentifier	22580007
schemaClass	LiteratureReference
title	Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast
url	http://www.ncbi.nlm.nih.gov/pubmed/22580007
volume	361
year	2012

Referrals

(literatureReference)

[Summation:9946364] Most postnatal mammary gland development originates from uni...
[CellLineagePath:R-HSA-9927418] Developmental Lineage of Mammary Gland Luminal Epithelial Cells
[Summation:9960185]
ESR+ luminal progenitors give rise to mature luminal cell...
[CellDevelopmentStep:R-HSA-9960183] Hormone receptor positive mammary luminal progenitor cell produces hormone receptor positive luminal epithelial cell
[Summation:9960172]
Colony-forming assays that use mammary stem-like cells (M...
[CellDevelopmentStep:R-HSA-9960175] Mammary stem cell produces hormone receptor positive luminal progenitor cell
[MarkerReference:9960170] EPCAM [plasma membrane] Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue
[MarkerReference:9960173] KRT18 mRNA [cytosol] The CD10 enzyme is a key player to identify and regulate human mammary stem cells
[MarkerReference:9960174] CD24 mRNA [cytosol] Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation
[MarkerReference:9960163] ITGA6(24-1130) [plasma membrane] Single Cell RNA Sequencing of Human Milk-Derived Cells Reveals Sub-Populations of Mammary Epithelial Cells with Molecular Signatures of Progenitor and Mature States: a Novel, Non-invasive Framework for Investigating Human Lactation Physiology
[MarkerReference:9960196] ESR1 mRNA [cytosol] Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
[MarkerReference:9960165] KRT19 [cytosol] The CD10 enzyme is a key player to identify and regulate human mammary stem cells
[MarkerReference:9960167] KRT19 mRNA [cytosol] Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast
[MarkerReference:9960156] MUC1 mRNA [cytosol] Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast
[MarkerReference:9960157] MUC1(24-1255) [plasma membrane] Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue
[MarkerReference:9960177] KRT18 [cytosol] The CD10 enzyme is a key player to identify and regulate human mammary stem cells
[MarkerReference:9960245] ESR1 [nucleoplasm] Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast
[Summation:9946416]
Colony-forming assays that use mammary stem-like cells (M...
[CellDevelopmentStep:R-HSA-9927428] Mammary stem cell produces hormone receptor negative luminal progenitor cell
[Summation:9925814]
This cell development step describes how mammary stem cel...
[MarkerReference:9945352] TP63-2 [nucleoplasm] Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiate
[MarkerReference:9941903] ITGA6(24-1130) [plasma membrane] Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue
[MarkerReference:9960205] PGR mRNA [cytosol] Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
[MarkerReference:9960195] ESR1 mRNA [cytosol] Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
[MarkerReference:9960240] PGR [nucleoplasm] Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast
[MarkerReference:9960242] ESR1 [nucleoplasm] Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast
[MarkerReference:9941898] MUC1(24-1255) [plasma membrane] Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue
[MarkerReference:9941891] EPCAM [plasma membrane] Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue
[MarkerReference:9946809] CD24 mRNA [cytosol] Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation
[MarkerReference:9959900] KRT19 mRNA [cytosol] Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast
[MarkerReference:9946844] KRT18 mRNA [cytosol] The CD10 enzyme is a key player to identify and regulate human mammary stem cells
[MarkerReference:9959921] MUC1 mRNA [cytosol] Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast
[MarkerReference:9946418] KRT19 [cytosol] The CD10 enzyme is a key player to identify and regulate human mammary stem cells
[MarkerReference:9959924] ITGA6(24-1130) [plasma membrane] Single Cell RNA Sequencing of Human Milk-Derived Cells Reveals Sub-Populations of Mammary Epithelial Cells with Molecular Signatures of Progenitor and Mature States: a Novel, Non-invasive Framework for Investigating Human Lactation Physiology
[MarkerReference:9946807] KRT18 [cytosol] The CD10 enzyme is a key player to identify and regulate human mammary stem cells

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