FBXL21, the substrate recognition component of the FBXL21:CU...

created [InstanceEdit:9933305] May, Bruce, 2024-12-28
dbId 9933325
displayName FBXL21, the substrate recognition component of the FBXL21:CU...
literatureReference
schemaClass Summation
text FBXL21, the substrate recognition component of the FBXL21:CUL1:SKP1:RBX1 SCF E3 ligase complex, binds phosphorylated CRY1 and CRY2 (inferred from mouse homologs). FBXL21, like FBXL3, binds the photolyase homology in the N-terminal region of CRY1 (inferred from mouse homologs). The interaction between FBXL21 and CRY1 is also observed in sheep (Dardente et al. 2008).
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