Reactome | Negative regulation by 'S-adenosyl-L-homocysteine [mitochondrial matrix]'

Schema > NegativeRegulation > Entries

created	[InstanceEdit:9861205] D'Eustachio, Peter, 2024-02-14
dbId	9861204
displayName	Negative regulation by 'S-adenosyl-L-homocysteine [mitochondrial matrix]'
modified	[InstanceEdit:9861206] D'Eustachio, Peter, 2024-02-14
regulatedEntity	[Reaction:R-PFA-9854315] CSKMT methylates Citrate Synthase - Plasmodium falciparum [Reaction:R-DRE-9854315] CSKMT methylates Citrate Synthase - Danio rerio [Reaction:R-SSC-9854315] CSKMT methylates Citrate Synthase - Sus scrofa [Reaction:R-BTA-9854315] CSKMT methylates Citrate Synthase - Bos taurus [Reaction:R-HSA-9854315] CSKMT methylates Citrate Synthase - Homo sapiens [Reaction:R-CFA-9854315] CSKMT methylates Citrate Synthase - Canis familiaris
regulator	[SimpleEntity:R-ALL-9854312] S-adenosyl-L-homocysteine [mitochondrial matrix]
schemaClass	NegativeRegulation

(regulatedBy)	[Reaction:R-PFA-9854315] CSKMT methylates Citrate Synthase [Reaction:R-DRE-9854315] CSKMT methylates Citrate Synthase [Reaction:R-SSC-9854315] CSKMT methylates Citrate Synthase [Reaction:R-BTA-9854315] CSKMT methylates Citrate Synthase [Reaction:R-HSA-9854315] CSKMT methylates Citrate Synthase [Reaction:R-CFA-9854315] CSKMT methylates Citrate Synthase
(regulation)	[RegulationReference:9861203] Negative regulation by 'S-adenosyl-L-homocysteine [mitochondrial matrix]' Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation