Activated PKR phosphorylates sphingosin kinase 1 (SPHK1) at ...
| created | [InstanceEdit:9836614] Stephan, Ralf, 2023-05-31 |
| dbId | 9836615 |
| displayName | Activated PKR phosphorylates sphingosin kinase 1 (SPHK1) at ... |
| modified | [InstanceEdit:9839458] Stephan, Ralf, 2023-07-06 |
| schemaClass | Summation |
| text | Activated PKR phosphorylates sphingosin kinase 1 (SPHK1) at S225 in the nucleus, priming it for nuclear export. This process is part of a feedback loop between PKR and SPHK1, activating pro-survival pathways in the cellular response to external stimuli (Qiao et al, 2020). |
Referrals
| (summation) |
© 2026 Reactome
