Reactome | 3'-5'-DNA exonuclease activity of MRN:CtIP [nucleoplasm]

Schema > CatalystActivity > Entries

activeUnit	[EntityWithAccessionedSequence:R-HSA-59544] MRE11A [nucleoplasm] - Homo sapiens
activity	[GO_MolecularFunction:23750] 3'-5'-DNA exonuclease activity
catalyzedEvent	[BlackBoxEvent:R-HSA-9023943] MRN:CtIP exonucleolytically hydrolyzes DNA 3' to SPO11 and SPO11:double-strand break dissociates to SPO11:oligonucleotide and resected 5' end - Homo sapiens
created	[InstanceEdit:981786] May, B, 2010-10-27
dbId	981788
displayName	3'-5'-DNA exonuclease activity of MRN:CtIP [nucleoplasm]
modified	[InstanceEdit:9909910] Weiser, Joel, 2024-05-14
physicalEntity	[Complex:R-HSA-981776] MRN:CtIP [nucleoplasm]
schemaClass	CatalystActivity

(catalystActivity)

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