Reactome | Negative regulation by 'IL6R:IL6R inhibitors [plasma membrane]'

Schema > NegativeRegulation > Entries

created	[InstanceEdit:9690520] Jassal, Bijay, 2020-06-02
dbId	9690521
displayName	Negative regulation by 'IL6R:IL6R inhibitors [plasma membrane]'
modified	[InstanceEdit:9715064] Stephan, Ralf, 2021-02-16
regulatedEntity	[Reaction:R-HSA-1067667] IL6 binds IL6R - Homo sapiens
regulator	[Complex:R-HSA-9681293] IL6R:IL6R inhibitors [plasma membrane]
schemaClass	NegativeRegulation

(regulation)	[RegulationReference:9690522] Negative regulation by 'IL6R:tocilizumab [plasma membrane]' Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: a randomized, double-blind, placebo-controlled, dose-escalation trial
(regulatedBy)	[Reaction:R-HSA-1067667] IL6 binds IL6R

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