Reactome | Requirement by 'MTO1 [mitochondrial matrix]'

Schema > Requirement > Entries

created	[InstanceEdit:9676136] May, Bruce, 2020-02-10
dbId	9676134
displayName	Requirement by 'MTO1 [mitochondrial matrix]'
regulatedEntity	[BlackBoxEvent:R-HSA-6787403] GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA - Homo sapiens
regulator	[EntityWithAccessionedSequence:R-HSA-6787379] MTO1 [mitochondrial matrix]
schemaClass	Requirement

(regulation)	[RegulationReference:9676135] Requirement by 'MTO1 [mitochondrial matrix]' MTO1 mediates tissue specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention
(regulatedBy)	[BlackBoxEvent:R-HSA-6787403] GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA

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