Comapred with the wild type ERBB2, ERBB2 G309E, ERBB2 S310F ...

created [InstanceEdit:9665475] Orlic-Milacic, Marija, 2019-10-31
dbId 9665477
displayName Comapred with the wild type ERBB2, ERBB2 G309E, ERBB2 S310F ...
schemaClass Summation
text Comapred with the wild type ERBB2, ERBB2 G309E, ERBB2 S310F and ERBB2 S310Y are more sensitive to tyrosine kinase inhibitors lapatinib, neratinib and afatinib (Greulich et al. 2012). ERBB2 G309A was also responsive to lapatinib and neratinib (Bose et al. 2013).
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