After phosphorylation of MAPKs by complexes containing RAF1 ...

created [InstanceEdit:9655942] Rothfels, Karen, 2019-07-27
dbId 9655943
displayName After phosphorylation of MAPKs by complexes containing RAF1 ...
schemaClass Summation
text After phosphorylation of MAPKs by complexes containing RAF1 mutants, activated MAPK signaling complexes dissociate in a manner similar to wildtype, although this has not been explicitly demonstrated in all cases. Active complexes may signal from other cellular locations or may amplify signaling through rounds of heterodimerization with other inactive RAF monomers (reviewed in Matallanas et al, 2011; Cseh et al, 2014).
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