Reactome | Negative regulation by 'KICSTOR:GATOR1:GATOR2 [lysosomal membrane]'

Schema > NegativeRegulation > Entries

activeUnit	[Complex:R-HSA-9638227] GATOR2 [lysosomal membrane] - Homo sapiens
created	[InstanceEdit:9645591] May, Bruce, 2019-05-13
dbId	9645590
displayName	Negative regulation by 'KICSTOR:GATOR1:GATOR2 [lysosomal membrane]'
modified	[InstanceEdit:9645601] May, Bruce, 2019-05-13
regulatedEntity	[Reaction:R-HSA-9640195] RRAGA,B hydrolyzes GTP - Homo sapiens
regulator	[Complex:R-HSA-9639281] KICSTOR:GATOR1:GATOR2 [lysosomal membrane]
schemaClass	NegativeRegulation

(regulation)	[RegulationReference:9647730] Negative regulation by 'KICSTOR:GATOR1:GATOR2 [lysosomal membrane]' A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1
(regulatedBy)	[Reaction:R-HSA-9640195] RRAGA,B hydrolyzes GTP

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