Reactome | Positive regulation by 'Hoxb1:Pbx1:Pknox1 at active Hoxa2 chromatin [nucleoplasm]' A regulatory module embedded in the coding region of Hoxa2 controls expression in rhombomere 2

Schema > RegulationReference > Entries

created	[InstanceEdit:9641190] Wu, G, 2019-04-04
dbId	9641848
displayName	Positive regulation by 'Hoxb1:Pbx1:Pknox1 at active Hoxa2 chromatin [nucleoplasm]' A regulatory module embedded in the coding region of Hoxa2 controls expression in rhombomere 2
literatureReference	[LiteratureReference:5619212] A regulatory module embedded in the coding region of Hoxa2 controls expression in rhombomere 2 [LiteratureReference:5619331] An ultraconserved Hox-Pbx responsive element resides in the coding sequence of Hoxa2 and is active in rhombomere 4 [LiteratureReference:5619332] Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila [LiteratureReference:5619162] Expression of Hoxa2 in rhombomere 4 is regulated by a conserved cross-regulatory mechanism dependent upon Hoxb1 [LiteratureReference:5621516] The Hoxa2 enhancer 2 contains a critical Hoxa2 responsive regulatory element
regulatedBy	[PositiveRegulation:R-MMU-5634095] Positive regulation by 'Hoxb1:Pbx1:Pknox1 at active Hoxa2 chromatin [nucleoplasm]'
schemaClass	RegulationReference

(regulationReference)

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