Activation of PI3K signaling downstream of NTRK3 (TRKC) is e...

created [InstanceEdit:9603477] Orlic-Milacic, Marija, 2018-03-21
dbId 9603474
displayName Activation of PI3K signaling downstream of NTRK3 (TRKC) is e...
schemaClass Summation
text Activation of PI3K signaling downstream of NTRK3 (TRKC) is evident from PI3K-dependent activating phosphorylation of AKT in response to NTRK3 activity. SRC and IRS1 contribute to NTRK3-mediated induction of PI3K activity, but the exact mechanism is not known (Tognon et al. 2001, Jin et al. 2008).
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